Inhibition of the Defense System Stimulating Interleukin-12 Interferon-γ Pathway During Critical Illness
نویسندگان
چکیده
منابع مشابه
Inhibition of the defense system stimulating interleukin-12 interferon-gamma pathway during critical Illness.
Interleukin-12 (IL-12) and interferon-gamma (IFN-gamma) exert protective effects during experimental endotoxemia through upregulation of cellular immunity and phagocytic functions. They are part of a positive regulatory feedback loop that enhances the production of the other. Because critically ill patients show a marked suppression of T-cell and macrophage functions with a high susceptibility ...
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ژورنال
عنوان ژورنال: Blood
سال: 1997
ISSN: 1528-0020,0006-4971
DOI: 10.1182/blood.v89.5.1612